About M.doc

Nampons contain a mild-clotting agent that has been used for over 50 years called "oxidized cellulose."   In Nampons, this technology is known as m•doc.

m•doc consists of 100% active substance – microdispersed oxidized cellulose, calcium/sodium salt (m.doc; calcium/sodium salt of copolymer of anhydroglucose (ß-D-glucopyranose) and anhydroglucuronic (ß -D-glucopyranuronic) acid).

m•doc Regulatory Summary

  • EU: Class I (non-sterile)
  • USA: Class 1 (CFR 878.4018) – 510(k) exempt
  • GMDN code: 10284 (Pressure bandage)

m•doc coated Nasal Plug Intended Use
m•doc is a powder intended to be used for the topical treatment of capillary and/or parenchymatous bleeding from surface injuries of traumatic origin and/or injuries artificially produced in the context of surgical intervention. It is intended to be sold by pharmacies as a nonprescription product for both surgeons and first- aid use.

m•doc Mechanism of Action
Oxidised cellulose is micronized through a proprietary process of a further oxidation step, hydrolysis and refinement.

m•doc activates the intrinsic system by interacting with individual coagulation enzymes and activating clot formation (specifically FXII). m•doc also activates platelets and forms a soft, gel-like matrix (scab) above the wound which prevents clots from washing away and promotes the clotting process. In addition, it provides a structural scaffold through a gel “plug” formation, which causes physical retardation of blood flow and absorbs fluid provides a surface for proteins and cells to adhere to and interact with.